![]() ![]() Hydrothermal processing decreased the polyphenol content in pulses by 50-85%, mainly due to leaching into the processing water. Swedish berries and pulses were found to be good sources of polyphenols. The results showed that the optimized analytical methods were capable of quantifying flavonoids in berries and pulses with high precision and recovery. Lingonberries, brown beans, and the isolated fractions were added to a high-fat diet and fed to Apoe -/- mice for 10.5 weeks, to determine their effects on atherosclerotic plaque amount, plasma lipids, gut microbiota, cecal short-chain fatty acids (SCFAs), and plasma methylamines. The fiber and flavonoid fractions from lingonberries and the fiber fraction from brown beans were isolated and evaluated for their in vivo effects on atherosclerosis, compared with whole lingonberries and brown beans. The method developed for flavonoid analysis, based on reversed phase HPLC-UV/MS, and extraction procedures were optimized for the berry and pulse matrices, and used to characterize the flavonoids in four Swedish berry species and polyphenols in eight Swedish pulse species (raw and cooked). The nutritional benefits of lingonberries, brown beans, and their polyphenol and fiber fractions, were then investigated in an Apoe -/- mouse model. ![]() The methods were used for characterization of polyphenols in Swedish berries and pulses. In this thesis, methods for quantification of flavonoids in berry and pulse matrices were developed. These nutritional benefits are often attributed to high content of polyphenols (flavonoids and phenolic acids) and dietary fiber. ![]() 2021 (English) Doctoral thesis, comprehensive summary (Other academic) Abstract Ĭonsumption of berries and pulses can protect against atherosclerosis and other metabolic diseases, by modulating plasma lipid profile, gut microbiota, and microbiota-dependent metabolites. ![]()
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